Fourth-placed Keighley, who have another Yorkshire Division One derby at Ilkley on Saturday, bring in centre Marco Ferrazano from the second team, Adam Horsfall dropping to the bench.
Ollie Sugden starts at prop, with Paul Sinfield on the bench.
Meanwhile, scrum half Andy Marklew has announced his retirement after suffering a chronic hip problem.
Keighley (at Ilkley): D McGee; L Uren, M Ferrazano, S Dyson, J Anson; A Brown, A Balderstone; C Spencer, W Armitage, O Sugden. D Lister, S Inman, N Thornton, D Pullen, L Sugden. Replacements: T Lowther, A Horsfall, P Sinfield.
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