MARKS & Spencer has entered its final week of trading at The Broadway in Bradford.
The major retailer's prominent store at the city shopping centre will close for good on May 18.
At this stage, it is not known what will replace it.
The M&S has been in The Broadway since it opened in 2015.
Vickie Smith, Marks & Spencer regional manager, told the Telegraph & Argus in April: "We would like to thank all customers who have shopped with us at our Bradford Broadway store.
"The store will close on May 18 and we are continuing discussions with colleagues about what this decision means for them.
"Wherever possible, we will offer them alternative roles with M&S.
"Shopping habits are changing and so we're rotating our store estate to make sure we have the right stores in the right place and with the right space.
"Bradford remains a hugely important city for M&S and, in the last 10 years, we've invested more than £120million in our Bradford distribution centre, which employs over 1,800 people.
"We have also invested £20m in recent years in our stores across West Yorkshire."
She said the company would continue to serve customers at Marks & Spencer branches at Bradford Royal Infirmary, Bingley, Ilkley - all Simply Food outlets - as well as Owlcotes at Pudsey, and online.
Ian Ward, general manager at The Broadway, said: "M&S closing its store at The Broadway is a loss for both the city centre and the wider Bradford district, and we are thinking of all those affected."
After the T&A revealed that the store would shut on May 18, many people got in touch to express their sadness.
Mark Cowgill, president of Bradford Chamber of Commerce, described the news as "disappointing".
He said: "As a key presence in the city, the decision to close is both surprising and disappointing, considering the company's commitment to growth in the local area.
"M&S must now deliver on their priority of protecting local jobs.
"With Bradford City of Culture 2025 next year, plus other investment projects happening across the city, this is an exciting time to operate in Bradford.
"We hope that the space left by the closure of M&S will be optimised by another business who can capitalise on this opportunity."
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